Calciphylaxis (kal-sih-fuh-LAK-sis) is a serious and rare disease in which calcium builds up in the small blood vessels of adipose and skin tissue.
- Calciphylaxis causes blood clots, painful skin ulcers, and can cause serious infections that can be fatal. People with calciphylaxis usually have kidney failure and have been dialyzed or had a kidney transplant. The condition can also occur in people without kidney disease.Calciphylaxis Treatment Nizamabad
The signs and symptoms of calciphylaxis are:Calciphylaxis Treatment Nizamabad
- Large purple reticulated patterns on the skin
- Deep, very painful bumps leading to open wounds with a blackish brown scab that does not heal – usually in areas of high fat skin such as the stomach and thighs, although they can appear anywhere
- Infections from non-healing wounds
The exact cause of calciphylaxis is unknown, but recent studies have shown that most people with the condition have abnormalities in blood clotting factors. Clotting factors are substances in your blood that help stop bleeding. These abnormalities can cause small blood clots to form more often than normal.
- In addition, people with calciphylaxis have an imbalance in calcium metabolism. This calcium, deposited in the smaller ones, causes parts of the arteries (arterioles), which eventually lead to the formation of blood clots in the arterioles. Blood clots can lead to a lack of oxygen and nutrition in adipose tissue and skin.
Calciphylaxis most commonly affects people with end-stage kidney disease. Possible risk factors are:Calciphylaxis Treatment Nizamabad
- Be a woman
- Blood clotting factor abnormalities
- Long-term dialysis and sometimes kidney transplant
- An imbalance of calcium, phosphorus and aluminum in the body