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Microscopic colitis is inflammation of the large intestine that causes persistent watery diarrhea. The disorder takes its name from the fact that it is necessary to examine colon tissue under a microscope to identify it, as the tissue may appear normal on a colonoscopy or flexible sigmoidoscopy.Microscopic colitis Treatment warangal
There are several subtypes of microscopic colitis:
- Collagen colitis, in which a thick layer of protein (collagen) grows in the colon tissue
- Lymphocytic colitis, in which white blood cells (lymphocytes) in the colon tissue increase
- Incomplete microscopic colitis, which has mixed features of collagen and lymphatic colitis.
symptom
The signs and symptoms of microscopic colitis include:Microscopic colitis Treatment warangal
- Chronic watery diarrhea
- Abdominal pain, cramps, or gas
- Weight loss
- nausea
- Fecal incontinence
- Dehydration
The reasons
It is not known what causes inflammation of the colon in microscopic colitis. Researchers believe the causes can be:Microscopic colitis Treatment warangal
- Medicines that can irritate the lining of the intestines.
- Bacteria that produce toxins that irritate the lining of the intestines.
- Viruses that cause inflammation.
- Autoimmune diseases associated with microscopic colitis, such as rheumatoid arthritis, celiac disease, or psoriasis. Autoimmune diseases occur when your body’s immune system attacks healthy tissue.
- Bile acid is not absorbed properly and irritates the intestinal lining.Microscopic colitis Treatment warangal
Risk factors
Risk factors for microscopic colitis are:Microscopic colitis Treatment warangal
- Age. Microscopic colitis is more common in people between the ages of 50 and 70.
- Sex. Women are more likely to have microscopic colitis than men. Some studies suggest a link between postmenopausal hormone therapy and microscopic colitis.
- Autoimmune disease. People with microscopic colitis also sometimes have an autoimmune disease such as celiac disease, thyroid disease, rheumatoid arthritis, type 1 diabetes, or psoriasis.
- Genetic connection. Research suggests that microscopic colitis may be related to a family history of irritable bowel syndrome.
- Smoke. Recent studies have shown a link between smoking and microscopic colitis, especially in people aged 16 to 44 years.