overview
Peripheral nerve sheath malignancy is a rare type of cancer that occurs in the lining of nerves that extend from the spinal cord through the body. Malignant tumors of the peripheral nerve sheath were called neurofibrosarcomas.
Malignant tumors of the peripheral nerve sheath can occur anywhere in the body, but most commonly in the deep tissues of the arms, legs, and trunk. They tend to cause pain and weakness in the affected area, and can also cause a growing lump or mass. Neurofibrosarcoma Treatment in Hyderabad
symptoms
Signs and symptoms of malignant tumors of the peripheral nerve sheath include:
- Pain in the affected area
- Weakness trying to move the affected part of the body
- A piece of tissue that grows under the skin
The reasons
It is not known what causes most malignant tumors of the peripheral nerve sheath.
Doctors know that these cancers start when a cell wrapping around a nerve develops a defect (mutation) in its DNA. The mutation tells the cell to multiply quickly and continue to live while other cells normally die. The cells that build up form a tumor that can grow to invade nearby tissue or spread to other areas of the body. Neurofibrosarcoma Treatment in Hyderabad
Risk factors
Factors that increase the risk of developing malignant tumors of the peripheral nerve sheath include:
- Previous radiation therapy for cancer. A malignant tumor of the peripheral nerve sheath may develop in the area treated with radiation 10 to 20 years after treatment.
- Not cancerous nerve tumors. Malignant tumors of the peripheral nerve sheath can develop from non-cancerous (benign) nerve tumors such as neurofibromas.
- A hereditary disease that increases the risk of nerve tumors. Malignant tumors of the peripheral nerve sheath are more common in people with neurofibromatosis 1. Neurofibrosarcoma Treatment in Hyderabad