Neuropathy, hereditary motor and sensory Treatment in Hyderabad


Charcot (Shahr-KOH) Marie-Tooth disease is a group of inherited diseases that cause nerve damage. This damage mainly affects the arms and legs (peripheral nerves). Charcot-Marie-Tooth disease is also known as hereditary motor and sensory neuropathy.

Charcot-Marie-Tooth disease results in smaller and weaker muscles. Loss of sensation, muscle twitching, and difficulty walking can also occur. Deformities of the foot such as hammers and high arches are also common. Symptoms usually start in the feet and legs, but can eventually affect your hands and arms.

Symptoms of Charcot-Marie-Tooth disease usually appear in adolescence or early adulthood, but can also develop in your forties. Neuropathy, hereditary motor and sensory Treatment in Hyderabad


The signs and symptoms of Charcot-Marie-Tooth disease can include:

The reasons

Charcot-Marie-Tooth disease is an inherited genetic disorder. It happens when there are mutations in the genes that affect the nerves in your feet, legs, hands, and arms.

Sometimes these mutations damage the nerves. Other mutations damage the protective layer that surrounds the nerve (myelin sheath). Both send weaker messages between your limbs and your brain. Neuropathy, hereditary motor and sensory Treatment in Hyderabad

Risk factors

Charcot-Marie-Tooth disease is inherited, so you are at a higher risk of developing the disease if someone in your immediate family has the disease.

Other causes of neuropathy such as diabetes can cause symptoms similar to Charcot-Marie-Tooth disease. These other conditions can also make Charcot-Marie-Tooth disease symptoms worse. Medicines such as vincristine (Marqibo), paclitaxel (Abraxane), and others can make symptoms worse. Be sure to tell your doctor about any medications you are taking.


The complications of Charcot-Marie-Tooth disease vary in severity from person to person. Foot abnormalities and difficulty walking are usually the most serious problems. Muscles can weaken and you can injure areas of the body that have decreased sensation.

Sometimes the muscles in your feet may not be receiving your brain’s signal to contract, making you more likely to trip and fall. And your brain may not be receiving pain reports from your feet. For example, if you’ve rubbed a blister on your toe, it may be infected without you even realizing it. Neuropathy, hereditary motor and sensory Treatment in Hyderabad

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