Primary biliary cholangitis Treatment in Hyderabad


When the biliary tract is damaged, the bile can move back to your liver and sometimes cause irreversible scars in the liver tissue (cirrhosis).

Primary biliary cholangitis is considered an autoimmune disease, which means that your body’s immune system mistakenly attacks healthy cells and tissues. Researchers believe that a combination of genetic and environmental factors causes the disease. It usually grows slowly. Medications can slow liver damage, especially if treatment is started early.


More than half of people with primary biliary cholangitis have no apparent symptoms at diagnosis. The disease can be diagnosed if blood tests are done for other reasons. Symptoms will eventually develop over the next five to 20 years. Those who show symptoms at diagnosis tend to have worse results.

Common early symptoms are:

The reasons

It is not known what causes primary biliary cholangitis. Many experts consider it an autoimmune disease in which the body turns on its own cells.

Inflammation of the liver in primary biliary cholangitis begins when certain types of white blood cells called T cells (T cells) build up in the liver. Normally, these immune cells recognize germs such as bacteria and help to defend them. However, in primary biliary cholangitis, they mistakenly destroy the healthy cells that line the small bile ducts in the liver.

The inflammation in the smaller ducts spreads and eventually damages other cells in the liver. When the cells die, they are replaced by scar tissue (fibrosis), which can lead to cirrhosis. Cirrhosis of the liver is scarring of the liver tissue that makes it difficult for your liver to function properly.

Risk factors

The following factors can increase your risk of developing primary biliary cholangitis:


By working together, you and your doctor can help prevent these specific complications:

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