overview
- Thalassemia (thal-uh-SEE-me-uh) is a congenital blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia and make you tired.
- If you have mild thalassemia you may not need treatment. However, more severe forms may require regular blood transfusions. There are steps you can take to deal with fatigue, such as: B. choose a healthy diet and exercise regularly. Thalassemia Treatment in Nizamabad
symptom
There are different types of thalassemia. The signs and symptoms you have will depend on the type and severity of your illness.
The signs and symptoms of thalassemia can include:
- Tired
- Weakness
- Pale or yellowish skin
- Facial bone deformities
- Slow growth
- Abdominal swelling
- Dark urine
The reasons
- Thalassemia is caused by mutations in the DNA of cells that produce hemoglobin – the substance in red blood cells that carries oxygen around your body. Mutations associated with thalassemia are passed on from parents to children.
- Hemoglobin molecules are made up of chains called alpha and beta chains that can be affected by mutations. In thalassemia, the production of alpha or beta chains is reduced, resulting in alpha thalassemia or beta thalassemia.
- In alpha thalassemia, the severity of your thalassemia depends on how many genetic mutations you inherit from your parents. The more genes that are mutated, the more severe your thalassemia is.
- In beta thalassemia, the severity of the thalassemia depends on which part of the hemoglobin molecule is affected. Thalassemia Treatment in Nizamabad
Risk factors
Factors that increase your risk for thalassemia include:
Family history of thalassemia. Thalassemia is transmitted from parents to children through mutated hemoglobin genes.
Some ancestors. Thalassemia is most common in African Americans, as well as people of Mediterranean and Southeast Asian descent.
prevention
- In most cases, you cannot prevent thalassemia. If you have thalassemia or have a thalassemia gene, you should consult a genetic counselor if you are planning on having children.
- There is a diagnostic form of assisted reproductive technology that tests an early embryo for genetic mutations associated with in vitro fertilization. This could help parents with thalassemia or with a defective hemoglobin gene have healthy babies.
- The procedure involves collecting mature eggs and fertilizing them with sperm in a bowl in a laboratory. Embryos are tested for defective genes and only those without genetic defects are implanted in the uterus. Thalassemia Treatment in Nizamabad