overview
Creutzfeldt-Jakob disease (YAH-kobe at KROITS) (CJD) is a degenerative disease of the brain that leads to dementia and ultimately death. The symptoms of Creutzfeldt-Jakob disease can be similar to those of other dementia-like diseases of the brain, such as Alzheimer’s disease. However, Creutzfeldt-Jakob disease usually progresses much faster. Variant CJD Treatment in Hyderabad
symptoms
Creutzfeldt-Jakob disease is usually characterized by rapid mental deterioration within a few months.
The first signs and symptoms are usually:
- Personality changes
- Memory loss
- Changed thinking
- Blurred vision or blindness
- insomnia
- In coordination
- Difficulty speaking
The reasons
- Images comparing a normal prion with a diseased prion
- How prions open the popup dialog
- Creutzfeldt-Jakob disease and its variants belong to a large group of diseases in humans and animals known as transmissible spongiform encephalopathies (TSEs). The name is derived from the spongy holes that are visible under the microscope and develop in the affected brain tissue.
Risk factors
- Autosomal dominant inheritance model
- Autosomal Dominant Inheritance PatternOpen Context Dialog
- Most cases of Creutzfeldt-Jakob disease occur for unknown reasons and no risk factors can be identified. However, some factors appear to be linked to different types of CJD:
Age. Sporadic CJD tends to develop later in life, usually around the age of 60. Familial CJD begins a little earlier, and vCJD has affected people at a much younger age, usually in their late twenties.
Genetically. People with familial CJD have a genetic mutation that causes the disease. To develop familial CJD, a child must have a copy of the mutated gene that is inherited from both parents. If you have the mutation, the chance of passing it on to your children is 50%.
Complications
Creutzfeldt-Jakob disease affects the brain and body considerably. CJD usually progresses quickly. Over time, people with CJD withdraw from their friends and family, and eventually lose the ability to recognize or relate to them. They also lose the ability to take care of themselves and many fall into a coma. The disease is still fatal.
prevention
There is no known way to prevent sporadic Creutzfeldt-Jakob disease (CJD). If you have a family history of neurological disorders, speaking with a genetic counselor may benefit you. He or she can help you clarify the risks associated with your situation. Variant CJD Treatment in Hyderabad
