overview
- Waldenstrom’s macroglobulinemia (mak-roe-glob-u-lih-NEE-me-uh) is a rare type of cancer that begins in white blood cells.
- If you have Waldenstrom’s macroglobulinemia, your bone marrow is making too many abnormal white blood cells to crowd out healthy blood cells. Abnormal white blood cells produce a protein that builds up in the blood, affecting blood flow and causing complications.
- Waldenstrom’s macroglobulinemia is considered a type of non-Hodgkin lymphoma. It is sometimes referred to as lymphoplasmacytic lymphoma. Waldenstrom macroglobulinemia Treatment in Nizamabad
symptom
Waldenstrom’s macroglobulinemia is slow to develop and may not cause signs and symptoms for many years.
When they do occur, signs and symptoms can include:
- Easy bruising
- Bleeding from the nose or gums
- Tired
- Weight loss
- Numbness in the hands or feet
- fever
- a headache
- shortness of breath
- The eyesight changes
- confusion
The reasons
It is not known what causes Waldenstrom’s macroglobulinemia.
Doctors know that the disease begins with an abnormal white blood cell that develops errors (mutations) in their genetic code. Errors tell the cell to continue to multiply rapidly.
Because cancer cells don’t mature and then die like normal cells, they build up, which ultimately destroys the production of healthy cells. In the bone marrow – the blood-producing soft tissue that fills the center of most bones – Waldenstrom’s macroglobulinemia cells displace healthy blood cells.
Waldenstrom’s macroglobulinemia cells keep trying to make antibodies like healthy white blood cells do, but instead they produce abnormal proteins that the body cannot use. Immunoglobulin M (IgM) protein builds up in the blood, impairs blood flow, and causes complications. Waldenstrom macroglobulinemia Treatment in Nizamabad
Risk factors
Factors that can increase your risk of Waldenstrom’s macroglobulinemia include:
- To be older. Waldenstrom’s macroglobulinemia can occur at any age, but is most commonly diagnosed in adults aged 65 and over.
- Be a man. Waldenstrom macroglobulinemia is more commonly diagnosed in men.
- Be white Whites are more likely to develop the disease than people of other races.
- Have a family history of lymphoma. If you have a parent diagnosed with Waldenstrom macroglobulinemia or another type of B-cell lymphoma, you may be at increased risk. Waldenstrom macroglobulinemia Treatment in Nizamabad